Well,I'm no expert-but I have cooked a tad o' packers in a 150/160 over the years.
I agree with reading the archives/Smokin' 101/search,etc.
The 150 cooks pretty moist and turns out a fine product without foil,etc.
I like to cook my packers fat side up in the 160.
As for kenny K,if you have plenty of sides,you are talking about 150lbs of packers, to be sure you are covered.
That's about two heavy cases,or three light ones.
That's about a load and a half for your 150.
If I was cooking at around 225º,I might foil at around 165º internal.
Seems like there is always at least one stubborn one that won't give up,and this way they usually will all come tender around 195º.
Figure on about 1 1/2 hrs/lb and you should be covered.
You can defat the juice from the foil and pour it back over your sliced brisket.
Hope this helps a little.