Smokeyone,
I'd say there are just as many if not more people that set it on 250 and leave it there. Or they start at 225, and bump it to 250 when they hit the plateau.
As far as 200 vs. 250 and the amount of smoke taken at both temps? Sounds like a good test to me. Take 2 pieces of "like meat" at "like weight", and do one at 200 degrees one day. The next day do the other at 250 degrees.
See how long it took each thermostat setting to get the internal temp to 140 degrees. I'm betting the time difference is less than you'd think. And if it is a longer period than expected one has to consider if the added time in the "danger zone" is worth the extra smoke.
Just a thought or 2, but it would be worth the test I think.