I own a SM150, the black steel (outside) version of the SM160 - your unit has twice the capacity but is fairly like mine.
You should find a button on the lower right of the control panel that has a cows head and says BRISKETS on it. Apply your rub, put in your wood, place the brisket fat side down on the middle shelf, close her up, turn on, hit that BRISKETS button and START and walk away. DO NOT open the smoker for 11 hours, check the meat for tenderness and temperature with a quick read digital thermometer, it should be ALMOST perfect, around 190. Half an hour later it should reach about 195, it may take a little longer, as Smokin' says "it's done when it's done". 195, that's when I like to pull and foil my brisket for the long rest that Chaplin Bill describes.
It's that simple. I usually start my brisket about 9pm and when I get the wife off to work it's almost time to check the smoker. Can't get any easier...